10 Jan

Beta Bionics Secures $63M as AI-Driven “Pancreas” Heads to Key Tests

Beta Bionics, a startup developing a medical device that monitors and manages blood sugar levels in diabetes patients, has closed $63 million to back late-stage clinical tests of its AI-powered technology.

The cash tops off a Series B round of funding announced last year. The Boston company, which counts diabetes drug giants Eli Lilly (NYSE: LLY) and Novo Nordisk (NYSE: NVO) among its investors and partners, says the capital will support Phase 3 studies of its device this year, and if all goes well, an application for FDA approval.

Beta Bionics’s device is designed to mimic the role of… Read more »

UNDERWRITERS AND PARTNERS

          

          

            

10 Jan

Inventor Unlocks Method to Turn Plant Sugars Into Environmentally-Friendly Fuel

For years, scientists and researchers have been working to extract sugar molecules in plant life, known as cellulose. However, until now, it has proven to be nearly impossible to extract these sugars in a clean and efficient manner because they are locked tightly in a plant’s cellular walls.

As CBS profiled on 60 Minutes, Marshall Medoff, an 81-year-old inventor in Massachusetts, has uncovered the secret to accessing plant cellulose and transforming the inedible plant life into environmentally-friendly fuel and other applications.

By reversing the way large electron accelerator machines typically operate, Medoff has been able to break biomass apart and convert plant sugars into environmentally-friendly ethanol, gasoline and jet fuel. According to an independent study, Medoff’s ethanol actually emits 77 percent less greenhouse gas emissions than regular corn ethanol.

The technology could be a gamechanger because the fuel could be put into existing gas station pumps easily, requiring very little change in consumer behavior. A driver would simply walk up to the pump and be able to put this environmentally-friendly fuel in his or her vehicle.

The reason plant cellulose is such an alluring option as an energy resource is because it is the most abundant biological material on earth.

“Cellulose is everywhere,” said Medoff in the interview with CBS 60 Minutes. “I mean, there’s just so much cellulose in the world and nobody had managed to use any of it.”

Medoff’s technology is also being used to create healthier sugar and plastics that can be programmed to disintegrate within a specific timeframe.

This is just one of many examples of how industrial biotechnology is enabling the production of a variety of biofuels, bioplastics and other bio-based products, and helping make our lives and environment cleaner, safer and healthier.

09 Jan

Beta Bionics Secures $63M as AI-Driven “Pancreas” Heads to Key Tests

Beta Bionics, a startup developing a medical device that monitors and manages blood sugar levels in diabetes patients, has closed $63 million to back late-stage clinical tests of its AI-powered technology.

The cash tops off a Series B round of funding announced last year. The Boston company, which counts diabetes drug giants Eli Lilly (NYSE: LLY) and Novo Nordisk (NYSE: NVO) among its investors and partners, says the capital will support Phase 3 studies of its device this year, and if all goes well, an application for FDA approval.

Beta Bionics’s device is designed to mimic the role of… Read more »

UNDERWRITERS AND PARTNERS

          

          

            

09 Jan

H2020-JTI-IMI2-2018-15-two-stage

[Source: http://ec.europa.eu/health/ageing/innovation/index_en.htm] Identifier: H2020-JTI-IMI2-2018-15-two-stagePillar: Societal ChallengesOpening Date: Deadline: Wed, 24 Oct 2018 17:00:00 (Brussels local time)Modification Date: Wed, 9 Jan 2019Latest information:
An overview of the evaluation results (flash call info – IMI2 Call 15 – first stage) is now available under the call ‘Additional documents’ tab

09 Jan

Inventor Unlocks Method to Turn Plant Sugars Into Environmentally-Friendly Fuel

For years, scientists and researchers have been working to extract sugar molecules in plant life, known as cellulose. However, until now, it has proven to be nearly impossible to extract these sugars in a clean and efficient manner because they are locked tightly in a plant’s cellular walls.

As CBS profiled on 60 Minutes, Marshall Medoff, an 81-year-old inventor in Massachusetts, has uncovered the secret to accessing plant cellulose and transforming the inedible plant life into environmentally-friendly fuel and other applications.

By reversing the way large electron accelerator machines typically operate, Medoff has been able to break biomass apart and convert plant sugars into environmentally-friendly ethanol, gasoline and jet fuel. According to an independent study, Medoff’s ethanol actually emits 77 percent less greenhouse gas emissions than regular corn ethanol.

The technology could be a gamechanger because the fuel could be put into existing gas station pumps easily, requiring very little change in consumer behavior. A driver would simply walk up to the pump and be able to put this environmentally-friendly fuel in his or her vehicle.

The reason plant cellulose is such an alluring option as an energy resource is because it is the most abundant biological material on earth.

“Cellulose is everywhere,” said Medoff in the interview with CBS 60 Minutes. “I mean, there’s just so much cellulose in the world and nobody had managed to use any of it.”

Medoff’s technology is also being used to create healthier sugar and plastics that can be programmed to disintegrate within a specific timeframe.

This is just one of many examples of how industrial biotechnology is enabling the production of a variety of biofuels, bioplastics and other bio-based products, and helping make our lives and environment cleaner, safer and healthier.

09 Jan

Foundation Medicine Appoints Roche’s Cindy Perettie CEO

Foundation Medicine has appointed Cindy Perettie to serve as its CEO. Perettie comes to Cambridge, MA-based Foundation from Roche, where she was a senior vice president in global oncology product strategy for the company’s oncology unit. Perettie will start at Foundation on Feb. 4 succeeding Troy Cox, who has been CEO for the past two years.

Foundation analyzes blood samples of cancer patients for genetic information that helps guide treatment decisions. Pharmaceutical companies also use Foundation’s technology to identify patients for clinical trials. Last year, Roche paid $2.4 billion to acquire the part of Foundation that it did not already Read more »

UNDERWRITERS AND PARTNERS

          

          

            

09 Jan

This Major Breakthrough Could Help Improve Global Food Supply

Researchers and scientists around the world have been working for years to engineer photosynthesis as a means to safely enhance crop productivity and improve the global food supply, and just this week, significant progress towards that objective occurred.

On Thursday, researchers at the University of Illinois announced they were successful in producing tobacco plants that were 40 percent larger.

Now, the goal of this endeavor is not to produce more tobacco. Instead, they are aiming to apply the technique to staple crops – such as tomatoes, soybeans and black-eyed peas – in an effort to meet the growing demand for food.

According to AFP News:

The scientists at the university’s Carl R. Woese Institute for Genomic Biology say they have found a way to make the process of photosynthesis, the process by which plants use sunlight to convert carbon dioxide and water into energy, inherently more efficient.

An enzyme called Rubisco is key to the process of converting atmospheric carbon into an organic compound the plant consumes, a process known as “carbon fixation.”

But the enzyme also acts to “fix” atmospheric oxygen, converting it into toxic compounds that the plant expends considerable energy eliminating – energy that could otherwise be spent in growing. This competing process is known as photorespiration.

The Illinois team came up with the idea of implanting bits of algae DNA into the tobacco plant’s cells to create a type of biological shortcut that would speed up photorespiration.

Lead author Donald Ort told AFP: “If you take a shortcut, when you’re driving your car, you travel less distance, and you use less fuel.”

When a plant uses less energy on photorespiration, it “is able to take that energy and put it into plant growth and plant productivity, rather than using it to metabolize this toxic compound.”

Other techniques had tried to limit photorespiration, but have often led to negative impacts on the plant’s other functions.

“What’s cool about this is that they’ve been very clever in targeting the pathway in a way that doesn’t cause side effects,” David Stern, president of the Boyce Thompson Institute, which was not a part of the study, told AFP.

Maureen Hanson, a professor of molecular biology and genetics at Cornell University, said this is “really the first major breakthrough showing that one can indeed engineer photosynthesis and achieve a major increase in crop productivity.”

The University of Illinois project is being funded by the U.S. Department of Agriculture as well as the Bill and Melinda Gates Foundation, which has been very active  in developing ways to utilize genetics as a means to transform global development, combat the looming food crisis, and fight deadly diseases.

 

08 Jan

Foundation Medicine Appoints Roche’s Cindy Perettie CEO

Foundation Medicine has appointed Cindy Perettie to serve as its CEO. Perettie comes to Cambridge, MA-based Foundation from Roche, where she was a senior vice president in global oncology product strategy for the company’s oncology unit. Perettie will start at Foundation on Feb. 4 succeeding Troy Cox, who has been CEO for the past two years.

Foundation analyzes blood samples of cancer patients for genetic information that helps guide treatment decisions. Pharmaceutical companies also use Foundation’s technology to identify patients for clinical trials. Last year, Roche paid $2.4 billion to acquire the part of Foundation that it did not already Read more »

UNDERWRITERS AND PARTNERS

          

          

            

08 Jan

Better Health and care, economic growth and sustainable health systems

[Source: http://ec.europa.eu/health/ageing/innovation/index_en.htm] Identifier: H2020-SC1-BHC-2018-2020Pillar: Societal ChallengesOpening Date: Deadline: Tue, 2 Oct 2018 17:00:00 (Brussels local time)Modification Date: Tue, 8 Jan 2019Latest information: An overview of the evaluation results of the second stage (flash call info) for the topic SC1-BHC-15-2018 that closed on 04 September 2018 is now available under the “Topic conditions and documents” section on the topic page.

08 Jan

This Major Breakthrough Could Help Improve Global Food Supply

Researchers and scientists around the world have been working for years to engineer photosynthesis as a means to safely enhance crop productivity and improve the global food supply, and just this week, significant progress towards that objective occurred.

On Thursday, researchers at the University of Illinois announced they were successful in producing tobacco plants that were 40 percent larger.

Now, the goal of this endeavor is not to produce more tobacco. Instead, they are aiming to apply the technique to staple crops – such as tomatoes, soybeans and black-eyed peas – in an effort to meet the growing demand for food.

According to AFP News:

The scientists at the university’s Carl R. Woese Institute for Genomic Biology say they have found a way to make the process of photosynthesis, the process by which plants use sunlight to convert carbon dioxide and water into energy, inherently more efficient.

An enzyme called Rubisco is key to the process of converting atmospheric carbon into an organic compound the plant consumes, a process known as “carbon fixation.”

But the enzyme also acts to “fix” atmospheric oxygen, converting it into toxic compounds that the plant expends considerable energy eliminating – energy that could otherwise be spent in growing. This competing process is known as photorespiration.

The Illinois team came up with the idea of implanting bits of algae DNA into the tobacco plant’s cells to create a type of biological shortcut that would speed up photorespiration.

Lead author Donald Ort told AFP: “If you take a shortcut, when you’re driving your car, you travel less distance, and you use less fuel.”

When a plant uses less energy on photorespiration, it “is able to take that energy and put it into plant growth and plant productivity, rather than using it to metabolize this toxic compound.”

Other techniques had tried to limit photorespiration, but have often led to negative impacts on the plant’s other functions.

“What’s cool about this is that they’ve been very clever in targeting the pathway in a way that doesn’t cause side effects,” David Stern, president of the Boyce Thompson Institute, which was not a part of the study, told AFP.

Maureen Hanson, a professor of molecular biology and genetics at Cornell University, said this is “really the first major breakthrough showing that one can indeed engineer photosynthesis and achieve a major increase in crop productivity.”

The University of Illinois project is being funded by the U.S. Department of Agriculture as well as the Bill and Melinda Gates Foundation, which has been very active  in developing ways to utilize genetics as a means to transform global development, combat the looming food crisis, and fight deadly diseases.