25 Jul

Nabriva Bolsters Antibiotics Pipeline with Zavante Acquisition

San Diego Map 1480x (Depositphotos © lucianmilasan)

Nabriva Therapeutics has acquired Zavante Therapeutics in a stock deal that brings to the antibiotics developer an FDA-ready drug.

Under the deal terms announced after the market close Tuesday, San Diego-based Zavante received an upfront payment of 8.2 million Nabriva (NASDAQ: NBRV) shares. Nabriva, which splits its operations between Ireland and King of Prussia, PA, finished the trading day at $3.30 per share, making that payment worth $27 million. If Zavante’s drug hits regulatory and commercial milestones, that company’s former shareholders stand to gain up to $97.5 million more.

Zavante’s lead drug candidate, an injectable form of fosfomycin (Contepo), has… Read more »

UNDERWRITERS AND PARTNERS

          

          

            

24 Jul

Nancy Hopkins Named Xconomy’s 2018 Lifetime Achievement Award Winner

We at Xconomy are excited to announce that we are honoring Nancy Hopkins, professor emerita at MIT, with our 2018 Lifetime Achievement Award. The award recognizes Hopkins’s career in genetics and cancer biology research, as well as her groundbreaking work advocating for women in science that sparked change and inspired many in both academia and industry. She will receive her award and give an acceptance speech at our annual Xconomy Awards gala on Sept. 5 in Boston. Here’s more on Hopkins’s career.

As an MIT biologist in the early 1990s, Nancy Hopkins (pictured) wanted more lab space, just 200… Read more »

UNDERWRITERS AND PARTNERS

          

          

            

24 Jul

Research Headlines – Could nanotechnoloy ‘rewire’ an injured spinal cord?

[Source: Research & Innovation] Innovative equipment has been developed to help patients regain control of limbs despite an injury that stops the transmission of signals through the spinal cord. But what if this transmission could actually be re-established? An EU-funded project is working on an innovative implant, but there is still a very long way to go.

24 Jul

Greenwood: America Leads in Biopharmaceutical Innovation. Let’s Keep It That Way.

Writing last week for Morning Consult, BIO President and CEO Jim Greenwood proposed several policy ideas for Washington lawmakers to consider as they look to further reform America’s tax code.

Our nation’s life sciences industry is thriving but other countries are adopting policies designed to attract biotechnology firms to their shores, and as a result, the U.S. is losing some of its competitive advantage. In fact, as shown in a recent report commissioned by the Information Technology and Innovation Foundation, American innovation has slowed in recent years as other countries have developed policies to encourage innovation abroad.

“Foreign nations are competing aggressively to attract more life sciences investment, including through tax incentives such as “patent boxes” (which tax patent revenues more favorably than other sources of commercial revenue), regulatory reforms to speed up drug approvals, and workforce and immigration policies designed to attract and educate top talent in the life sciences field,” Greenwood warns.

Luckily, the ball is in our court. With Congress signaling that another round of changes to the tax code is in the works, adopting relatively simple changes can help cement U.S. leadership in the biosciences for generations to come.  Here’s a sample of what BIO recommends:

  • Reforming Section 382 of the tax code to help small biotechs further invest in the growth of their companies;
  • Simplifying Section 1202 of the tax code to encourage investment in innovative breakthroughs; and
  • Enabling more innovative startups to benefit from the payroll R&D credit in Section 41 of the Tax Code.

Read the full op-ed in Morning Consult here, and check out BIO’s recent letter to tax writers in the U.S. House of Representatives for a deeper dive on this important issue.

24 Jul

Bristol-Myers Squibb Executive Murdo Gordon Set to Depart

Murdo Gordon, chief commercial officer of Bristol-Myers Squibb (NYSE: BMS), is leaving. The New York-based pharmaceutical giant announced Monday that Gordon would depart on Aug. 3 “to pursue another opportunity.” No other details were given. According to a securities filing, Gordon notified the company of his plans on July 17. Before starting as Bristol’s chief commercial officer in 2016, Gordon held several executive roles at the company including senior vice president of oncology and immunology, and president of U.S. pharmaceuticals. Bristol said an announcement regarding Gordon’s successor would be made at a later date.

UNDERWRITERS AND PARTNERS

          

          

            

23 Jul

Sanofi Backs Click Therapeutics as Digital Medicines Gain Momentum

Drug makers are making more bets on the nascent field of digital medicine. The latest example: Click Therapeutics announced Monday that it grabbed a $17 million investment led by Sanofi Ventures, the Cambridge, MA-based venture capital arm of the French pharmaceutical giant.

New York-based Click Therapeutics develops mobile apps intended to be prescribed by doctors to treat medical conditions, either on their own or in tandem with drugs or other standard treatments. The six-year-old company is working on software that delivers cognitive and “neurobehavioral” exercises, aimed at treating depression, insomnia, acute coronary syndrome, and chronic pain. Click said it plans to… Read more »

UNDERWRITERS AND PARTNERS

          

          

            

23 Jul

Interdisciplinarity and the future of multilingualism research – 28-29 August 2018, Berlin, Germany

[Source: Research & Innovation] The final MIME conference on INTERDISCIPLINARITY AND THE FUTURE OF MULTILINGUALISM RESEARCH proposes to discuss the challenges of interdisciplinary cooperation and exchange in research on multilingualism and language policy and planning, with an emphasis on epistemological and methodological issues.

23 Jul

A New NAS Report Says Gene Editing is a “Breakthrough Opportunity”

There’s a huge opportunity to improve agriculture with gene editing. But we need to give CRISPR a chance, writes Tamar Haspel in Vox.

The National Academies of Sciences, Engineering, and Medicine last week released a report on how to address the most pressing problems of American agriculture. The list of those problems is long and scary: climate change, food waste, water scarcity, food-borne illness, pests, and disease.

The report identifies five scientific tools to improve sustainability and resilience, and four of them are pretty uncontroversial: understanding soil microbes, deploying sensors, integrating systems, and managing data. The fifth is gene editing. If the past is a predictor, that one will raise hackles. Nothing in agriculture is as divisive as a modified genome.

But does the past have to be a predictor? Is it possible that new gene editing techniques like CRISPR – along with new applications, new players, and a new way of talking with the public – give science the chance to press the reset button on genetic modification?

We can argue about the impact of the genetically modified organisms, or GMOs, already in our system, modified to be toxic to insects, resistant to herbicides, or both. It’s been a mixed bag, with decreases in insecticide and our most toxic herbicides on the plus side, and an increase in herbicide-tolerant weeds on the minus side.

But the argument against GMOs has never been just about the GMOs themselves. It is about a corporate-dominated, industrialized food system that’s focused on animal feed, processed foods, and biofuels and insufficiently attentive to soil health, environmental degradation, and biodiversity. GMOs have been a convenient handhold on a big, slippery problem. Enter CRISPR, a powerful new gene editing tool that’s everything GMOs aren’t.

Haspel explains: “For one, CRISPR is academic where GMO is corporate…It’s also transparent where GMO is opaque…It’s cheap where GMO is expensive…It’s accessible where GMO is proprietary.”

CRISPR may not win minds and hearts overnight, and we still have much to study and learn about it. But here’s hoping that transparency, community involvement, and applications in the public interest will bring gene editing skeptics to the table – disbelief at least temporarily suspended – to give it a chance.

20 Jul

GMO Answers LIVE at IFT 2018

Each year, the Institute of Food Technologists (IFT) holds their annual meeting and expo.  Since 1939, IFT has been bringing the most creative minds in the science of food and technology together to collaborate, learn, and contribute, all with the goal of inspiring and transforming collective scientific knowledge into innovative solutions for the benefit of all people around the world. IFT’s annual event and Food Expo is an excellent way to be one of the first to see some of the latest advancements and innovations in the science of food. Leading researchers and industry representatives come to IFT’s annual event to share their discoveries and soon to be released products. This year, more than 23,000 attendees were in Chicago to take in the educational sessions, networking opportunities, and walk the exhibit hall.

GMO Answers was there to talk to meeting attendees, including food scientists, buyers, food company executives, and students about GMOs. We also attended several sessions, including “The Clash Between Consumer Demands and Responsible Food” and “Embracing Agricultural Coexistence: Organic, Conventional, and Biotechnology.”

GMO Answers volunteer expert and farmer Katie Pratt held a Facebook Live chat during the show to talk about her three top takeaways:

  1. Food scientists overwhelmingly support GMO technologies and are looking for tools to be able to talk to the public about them.
  2. There is a disconnect between food scientists, nutritionists, dietitians on the R&D side of food companies and the marketing side, who are much more driven by trends and perceived consumer demand.
  3. Ultimately, farmers, scientists, and food companies all want the same thing: to provide healthy, safe, and affordable food to all.

Check out Katie’s Facebook Live to learn more about our experience at #IFT18.