30 Dec

4 Facts About Using Genetics in Pursuit of a More Perfect Christmas Tree

What will your Christmas gifts be placed under this year? A Fraser fir? A Douglas fir? An artificial tree?

While some individuals love the look and smell of a real Christmas tree, others prefer the low upkeep and longevity of an artificial tree.

But what if we could use genetics to improve the Christmas tree? Would you trade in the fake tree for a fir that loses less needles and requires less upkeep?

Here are four facts about using genetics in pursuit of a more perfect Christmas tree:

1) Very little has been known about the genomes of Christmas trees. Megan Molteni of Wired reported last year:

“…the conifer genome is not just enormous-20 billion base pairs compared to your 3 billion-but also pretty weird. At some point in their deep past, spruces, pines, firs, and their relatives acquired a complete second set of genes. Scientists think this genome-wide duplication likely helped shape these species into the tallest, hardiest plants in the world. But it’s also made sequencing them an incredibly daunting challenge. And unlike corn and soybean, there hasn’t been much money available to even try. So far scientists have managed to put together partial DNA blueprints for only a handful of conifers, not including the most popular Christmas tree species.”

2) Scientists and researchers are studying genetic data taken from Christmas trees around the world to better understand the DNA of these trees and increase the potential for genetic improvement. For example, North Carolina State University’s Christmas Tree Genetics Program has been working since 1996 to advance the state’s Christmas tree industry through the application of genetic principles.

“We are doing DNA sequencing to understand the DNA of Christmas trees, and in the long term, this may lead in the future to genetic engineering.” – John Frampton, professor in the department of Forestry and Environmental Resources at North Carolina State University

3) Genetics research could lead to the development of Fraser firs that are resistant to pests like Phytophthora root rot and the balsam woolly adelgid. A Christmas tree spends six to 10 years growing before it is cut to be sold, and such pests can kill a tree before that time.

Phytophthora is a fungus-like organism that can infect a Fraser fir and cause yellow-green needles, wilting, dead branches, and eventually tree death.

Balsam woolly adelgid is a small insect that feeds on Fraser firs and kills the trees after several years of infestation.

4) Genetics research is also exploring what separates the best needle-holders from the worst. Using branches from different trees, Gary Chastenger, a plant pathologist at Washington State University, has been researching the genetic variations of trees and needle retention. Via Wired:

Today, Chastagner’s team hangs the branches on racks or wire clotheslines strung across a temperature-controlled concrete cistern, where they rest without water for seven to 10 days. Then, a few well-trained technicians gently rub each branch and rate the needle retention on a scale of one (1 percent of needles fall off) to seven (91 to 100 percent loss).

Chastagner is only interested in the extremes on both sides of the spectrum. Over the years, he’s taken any cuttings that rate zero to one, or six to seven and grafted little bits of them onto rootstocks his lab manages on 15 acres in Puyallup. This process converts each outlying specimen into an isolated stand of genetically identical trees, preserving their unique DNA in what’s called a clonal holding block.

Now, those trees are part of a massive effort to pinpoint the tiny genetic variations that determine why some trees turn out better than others.

Six years ago, Chastagner and researchers at Washington State University, North Carolina State University and University of California, Davis jointly secured $1.3 million in funding from the U.S. Department of Agriculture to find genetic markers for Phytophthora root rot resistance and needle retention.

Chastagner’s graduate student, Katie McKeever, is collecting isolates of Phytophthora in various growing areas. By sequencing these samples and conducting pathogenicity trials, McKeever will contribute critical information to the team’s search for mechanisms of resistance in trees. Once the researchers find the relevant genetic markers, they can screen adult trees and select the most promising as seed sources for viable Christmas tree plantations.

The team will use similar techniques to resolve the matter of needle shedding. Chastagner’s multi-decade cataloging of Christmas trees with varying degrees of postharvest needle retention will give this part of the project a jump-start. By using these and other trees, scientists will be able to quickly identify needle-retentive gene sources so growers can produce desirable Christmas trees.

Through genetics research we can improve firs that are used for Christmas trees and ensure the genetic conservation of firs. There is much more to learn about conifer genetics, but as Chastagner said in the interview with Wired, “the potential for genetic improvement in these species is huge.”

29 Dec

From Alnylam to Zayner: Xconomy’s Top Innovation Stories of 2018

2018 was a year of ups and downs for the business and technology community. It was a year of big exits-both IPOs and acquisitions-for tech and life sciences companies. Venture funding remained strong, but more money went to fewer (and later-stage) companies overall. As the year winds down, we’re reflecting on the big innovation trends and developments that will carry over to next year.

Storylines in various sectors helped shape the overall narrative in 2018. Cell and gene therapies, cancer immunotherapy, and digital medicines made substantial progress in healthcare. Artificial intelligence and cybersecurity remained front and center in tech, as new… Read more »

UNDERWRITERS AND PARTNERS

          

          

            

29 Dec

4 Facts About Using Genetics in Pursuit of a More Perfect Christmas Tree

What will your Christmas gifts be placed under this year? A Fraser fir? A Douglas fir? An artificial tree?

While some individuals love the look and smell of a real Christmas tree, others prefer the low upkeep and longevity of an artificial tree.

But what if we could use genetics to improve the Christmas tree? Would you trade in the fake tree for a fir that loses less needles and requires less upkeep?

Here are four facts about using genetics in pursuit of a more perfect Christmas tree:

1) Very little has been known about the genomes of Christmas trees. Megan Molteni of Wired reported last year:

“…the conifer genome is not just enormous-20 billion base pairs compared to your 3 billion-but also pretty weird. At some point in their deep past, spruces, pines, firs, and their relatives acquired a complete second set of genes. Scientists think this genome-wide duplication likely helped shape these species into the tallest, hardiest plants in the world. But it’s also made sequencing them an incredibly daunting challenge. And unlike corn and soybean, there hasn’t been much money available to even try. So far scientists have managed to put together partial DNA blueprints for only a handful of conifers, not including the most popular Christmas tree species.”

2) Scientists and researchers are studying genetic data taken from Christmas trees around the world to better understand the DNA of these trees and increase the potential for genetic improvement. For example, North Carolina State University’s Christmas Tree Genetics Program has been working since 1996 to advance the state’s Christmas tree industry through the application of genetic principles.

“We are doing DNA sequencing to understand the DNA of Christmas trees, and in the long term, this may lead in the future to genetic engineering.” – John Frampton, professor in the department of Forestry and Environmental Resources at North Carolina State University

3) Genetics research could lead to the development of Fraser firs that are resistant to pests like Phytophthora root rot and the balsam woolly adelgid. A Christmas tree spends six to 10 years growing before it is cut to be sold, and such pests can kill a tree before that time.

Phytophthora is a fungus-like organism that can infect a Fraser fir and cause yellow-green needles, wilting, dead branches, and eventually tree death.

Balsam woolly adelgid is a small insect that feeds on Fraser firs and kills the trees after several years of infestation.

4) Genetics research is also exploring what separates the best needle-holders from the worst. Using branches from different trees, Gary Chastenger, a plant pathologist at Washington State University, has been researching the genetic variations of trees and needle retention. Via Wired:

Today, Chastagner’s team hangs the branches on racks or wire clotheslines strung across a temperature-controlled concrete cistern, where they rest without water for seven to 10 days. Then, a few well-trained technicians gently rub each branch and rate the needle retention on a scale of one (1 percent of needles fall off) to seven (91 to 100 percent loss).

Chastagner is only interested in the extremes on both sides of the spectrum. Over the years, he’s taken any cuttings that rate zero to one, or six to seven and grafted little bits of them onto rootstocks his lab manages on 15 acres in Puyallup. This process converts each outlying specimen into an isolated stand of genetically identical trees, preserving their unique DNA in what’s called a clonal holding block.

Now, those trees are part of a massive effort to pinpoint the tiny genetic variations that determine why some trees turn out better than others.

Six years ago, Chastagner and researchers at Washington State University, North Carolina State University and University of California, Davis jointly secured $1.3 million in funding from the U.S. Department of Agriculture to find genetic markers for Phytophthora root rot resistance and needle retention.

Chastagner’s graduate student, Katie McKeever, is collecting isolates of Phytophthora in various growing areas. By sequencing these samples and conducting pathogenicity trials, McKeever will contribute critical information to the team’s search for mechanisms of resistance in trees. Once the researchers find the relevant genetic markers, they can screen adult trees and select the most promising as seed sources for viable Christmas tree plantations.

The team will use similar techniques to resolve the matter of needle shedding. Chastagner’s multi-decade cataloging of Christmas trees with varying degrees of postharvest needle retention will give this part of the project a jump-start. By using these and other trees, scientists will be able to quickly identify needle-retentive gene sources so growers can produce desirable Christmas trees.

Through genetics research we can improve firs that are used for Christmas trees and ensure the genetic conservation of firs. There is much more to learn about conifer genetics, but as Chastagner said in the interview with Wired, “the potential for genetic improvement in these species is huge.”

29 Dec

From Alnylam to Zayner: Xconomy’s Top Innovation Stories of 2018

2018 was a year of ups and downs for the business and technology community. It was a year of big exits-both IPOs and acquisitions-for tech and life sciences companies. Venture funding remained strong, but more money went to fewer (and later-stage) companies overall. As the year winds down, we’re reflecting on the big innovation trends and developments that will carry over to next year.

Storylines in various sectors helped shape the overall narrative in 2018. Cell and gene therapies, cancer immunotherapy, and digital medicines made substantial progress in healthcare. Artificial intelligence and cybersecurity remained front and center in tech, as new… Read more »

UNDERWRITERS AND PARTNERS

          

          

            

29 Dec

4 Facts About Using Genetics in Pursuit of a More Perfect Christmas Tree

What will your Christmas gifts be placed under this year? A Fraser fir? A Douglas fir? An artificial tree?

While some individuals love the look and smell of a real Christmas tree, others prefer the low upkeep and longevity of an artificial tree.

But what if we could use genetics to improve the Christmas tree? Would you trade in the fake tree for a fir that loses less needles and requires less upkeep?

Here are four facts about using genetics in pursuit of a more perfect Christmas tree:

1) Very little has been known about the genomes of Christmas trees. Megan Molteni of Wired reported last year:

“…the conifer genome is not just enormous-20 billion base pairs compared to your 3 billion-but also pretty weird. At some point in their deep past, spruces, pines, firs, and their relatives acquired a complete second set of genes. Scientists think this genome-wide duplication likely helped shape these species into the tallest, hardiest plants in the world. But it’s also made sequencing them an incredibly daunting challenge. And unlike corn and soybean, there hasn’t been much money available to even try. So far scientists have managed to put together partial DNA blueprints for only a handful of conifers, not including the most popular Christmas tree species.”

2) Scientists and researchers are studying genetic data taken from Christmas trees around the world to better understand the DNA of these trees and increase the potential for genetic improvement. For example, North Carolina State University’s Christmas Tree Genetics Program has been working since 1996 to advance the state’s Christmas tree industry through the application of genetic principles.

“We are doing DNA sequencing to understand the DNA of Christmas trees, and in the long term, this may lead in the future to genetic engineering.” – John Frampton, professor in the department of Forestry and Environmental Resources at North Carolina State University

3) Genetics research could lead to the development of Fraser firs that are resistant to pests like Phytophthora root rot and the balsam woolly adelgid. A Christmas tree spends six to 10 years growing before it is cut to be sold, and such pests can kill a tree before that time.

Phytophthora is a fungus-like organism that can infect a Fraser fir and cause yellow-green needles, wilting, dead branches, and eventually tree death.

Balsam woolly adelgid is a small insect that feeds on Fraser firs and kills the trees after several years of infestation.

4) Genetics research is also exploring what separates the best needle-holders from the worst. Using branches from different trees, Gary Chastenger, a plant pathologist at Washington State University, has been researching the genetic variations of trees and needle retention. Via Wired:

Today, Chastagner’s team hangs the branches on racks or wire clotheslines strung across a temperature-controlled concrete cistern, where they rest without water for seven to 10 days. Then, a few well-trained technicians gently rub each branch and rate the needle retention on a scale of one (1 percent of needles fall off) to seven (91 to 100 percent loss).

Chastagner is only interested in the extremes on both sides of the spectrum. Over the years, he’s taken any cuttings that rate zero to one, or six to seven and grafted little bits of them onto rootstocks his lab manages on 15 acres in Puyallup. This process converts each outlying specimen into an isolated stand of genetically identical trees, preserving their unique DNA in what’s called a clonal holding block.

Now, those trees are part of a massive effort to pinpoint the tiny genetic variations that determine why some trees turn out better than others.

Six years ago, Chastagner and researchers at Washington State University, North Carolina State University and University of California, Davis jointly secured $1.3 million in funding from the U.S. Department of Agriculture to find genetic markers for Phytophthora root rot resistance and needle retention.

Chastagner’s graduate student, Katie McKeever, is collecting isolates of Phytophthora in various growing areas. By sequencing these samples and conducting pathogenicity trials, McKeever will contribute critical information to the team’s search for mechanisms of resistance in trees. Once the researchers find the relevant genetic markers, they can screen adult trees and select the most promising as seed sources for viable Christmas tree plantations.

The team will use similar techniques to resolve the matter of needle shedding. Chastagner’s multi-decade cataloging of Christmas trees with varying degrees of postharvest needle retention will give this part of the project a jump-start. By using these and other trees, scientists will be able to quickly identify needle-retentive gene sources so growers can produce desirable Christmas trees.

Through genetics research we can improve firs that are used for Christmas trees and ensure the genetic conservation of firs. There is much more to learn about conifer genetics, but as Chastagner said in the interview with Wired, “the potential for genetic improvement in these species is huge.”

28 Dec

From Alnylam to Zayner: Xconomy’s Top Innovation Stories of 2018

2018 was a year of ups and downs for the business and technology community. It was a year of big exits-both IPOs and acquisitions-for tech and life sciences companies. Venture funding remained strong, but more money went to fewer (and later-stage) companies overall. As the year winds down, we’re reflecting on the big innovation trends and developments that will carry over to next year.

Storylines in various sectors helped shape the overall narrative in 2018. Cell and gene therapies, cancer immunotherapy, and digital medicines made substantial progress in healthcare. Artificial intelligence and cybersecurity remained front and center in tech, as new… Read more »

UNDERWRITERS AND PARTNERS

          

          

            

28 Dec

Get a FREE Video Game Layout Pack for Divi

Hey Divi Nation! Thanks for joining us for the next installment of our weekly Divi Design Initiative where each week, we give away two brand new, free Divi Layout Packs from our design team to you.

This time around, Kenny and his team have created a gorgeous Gaming Layout Pack with amazing free illustrations that you’ll want to lay your hands on.

divi layout

Check Out The Divi Video Game

Layout Pack Below

Get it for free today!

gaming layout pack

Landing Page Design

gaming layout pack

View The Live Layout Demo

Home Page Design

gaming layout pack

View The Live Layout Demo

About Page Design

gaming layout pack

View The Live Layout Demo

Blog Page Design

gaming layout pack

View The Live Layout Demo

Coming Soon Page Design

gaming layout pack

View The Live Layout Demo

Community Page Design

gaming layout pack

View The Live Layout Demo

Support Page Design

gaming layout pack

View The Live Layout Demo

Key Features

The Video Game Layout Pack is ready to take your video game website to the next level. It includes amazing illustrations, a dark color palette and some of Divi’s finest design combinations. In other words; this layout pack will undeniably do justice to any website you decide to create.

Live Demos

Click the links below to see a live demo for each of the layouts included in the pack.

  1. Video Game Landing Page (live demo)
  2. Video Game Homepage (live demo)
  3. Video Game About Page (live demo)
  4. Video Game Blog Page (live demo)
  5. Video Game Coming Soon Page (live demo)
  6. Video Game Community Page (live demo)
  7. Video Game Support Page (live demo)

Access This Layout Right Now

Directly from Your Divi Builder

Subscribe To Our Youtube Channel

Since Version 3.0.99 of Divi, you can find and import any of the layouts included in this pack (along with ALL of Divi’s Premade Layout packs) directly from the Divi Builder. They are already waiting for you.

When you add a new page from the WordPress Dashboard, deploy the Visual Builder. You will be prompted with three choices regarding how you want to start building your page. Select the option “Choose A Premade Layout”.

Under the Premade Layouts tab, you can easily find the new layout by scrolling through the list of layout packs. Once you find the Layout Pack, click on it. You will see all the individual page layouts included in the pack. Select the page layout you want to use and then click the “Use This Layout” button.

video game layout pack

You can also access new layouts at anytime within the Visual Builder by clicking the “Load From Library” icon in the page settings bar (it looks like a plus symbol). Inside the Load From Library popup you can choose the new layout you want to use.

Authentication Required

Before you can download Premade Layouts from the Divi Library you must authenticate your Elegant Themes Subscription. If you have already activated updates for Divi under Divi > Theme Options > Updates, you have already authenticated your subscription and will have access to the layouts without a problem. If not, when you click to import a layout to your page, you will be prompted to enter your Elegant Themes Membership Username and API Key.

gaming layout pack

After you enter the Username and API Key, you will gain immediate access to the layouts. You can find your API Key under your members area on the Elegant Themes site.

No Licensing Restrictions

gaming layout pack

The photos included with these layouts have no licensing restrictions. This means you can use them in all of your commercial projects without having to worry about paying licensing fees or attributing the photographer. Use them in your commercial websites, sell them within your Divi child themes, include them in your own Divi layout packs or just use them on your blog. We know how challenging it can be to find good photos and how confusing and scary the licensing that governs those photos can be. We want to fix that problem for our users.

Download the Full Res Image Assets

New Layout Packs Every Week!

We hope you enjoy this layout pack. We look forward to hearing your opinions in the comment section below. Make sure you check out next week’s layout packs as well. We publish one on Monday and the other on Friday!

The post Get a FREE Video Game Layout Pack for Divi appeared first on Elegant Themes Blog.

28 Dec

Building a climate-neutral Europe with natural bio-based construction materials – 29 January 2019, Brussels, Belgium

[Source: Research & Innovation] To debate policies and initiatives to promote the use of innovative materials to decarbonise construction the ISOBIO Horizon 2020 project partners invite policy makers, industry, civil society groups and all interested stakeholders to an event on 29 January in Brussels. The event is free of charge, but registration is mandatory. A networking drinks reception will follow the event

28 Dec

4 Facts About Using Genetics in Pursuit of a More Perfect Christmas Tree

What will your Christmas gifts be placed under this year? A Fraser fir? A Douglas fir? An artificial tree?

While some individuals love the look and smell of a real Christmas tree, others prefer the low upkeep and longevity of an artificial tree.

But what if we could use genetics to improve the Christmas tree? Would you trade in the fake tree for a fir that loses less needles and requires less upkeep?

Here are four facts about using genetics in pursuit of a more perfect Christmas tree:

1) Very little has been known about the genomes of Christmas trees. Megan Molteni of Wired reported last year:

“…the conifer genome is not just enormous-20 billion base pairs compared to your 3 billion-but also pretty weird. At some point in their deep past, spruces, pines, firs, and their relatives acquired a complete second set of genes. Scientists think this genome-wide duplication likely helped shape these species into the tallest, hardiest plants in the world. But it’s also made sequencing them an incredibly daunting challenge. And unlike corn and soybean, there hasn’t been much money available to even try. So far scientists have managed to put together partial DNA blueprints for only a handful of conifers, not including the most popular Christmas tree species.”

2) Scientists and researchers are studying genetic data taken from Christmas trees around the world to better understand the DNA of these trees and increase the potential for genetic improvement. For example, North Carolina State University’s Christmas Tree Genetics Program has been working since 1996 to advance the state’s Christmas tree industry through the application of genetic principles.

“We are doing DNA sequencing to understand the DNA of Christmas trees, and in the long term, this may lead in the future to genetic engineering.” – John Frampton, professor in the department of Forestry and Environmental Resources at North Carolina State University

3) Genetics research could lead to the development of Fraser firs that are resistant to pests like Phytophthora root rot and the balsam woolly adelgid. A Christmas tree spends six to 10 years growing before it is cut to be sold, and such pests can kill a tree before that time.

Phytophthora is a fungus-like organism that can infect a Fraser fir and cause yellow-green needles, wilting, dead branches, and eventually tree death.

Balsam woolly adelgid is a small insect that feeds on Fraser firs and kills the trees after several years of infestation.

4) Genetics research is also exploring what separates the best needle-holders from the worst. Using branches from different trees, Gary Chastenger, a plant pathologist at Washington State University, has been researching the genetic variations of trees and needle retention. Via Wired:

Today, Chastagner’s team hangs the branches on racks or wire clotheslines strung across a temperature-controlled concrete cistern, where they rest without water for seven to 10 days. Then, a few well-trained technicians gently rub each branch and rate the needle retention on a scale of one (1 percent of needles fall off) to seven (91 to 100 percent loss).

Chastagner is only interested in the extremes on both sides of the spectrum. Over the years, he’s taken any cuttings that rate zero to one, or six to seven and grafted little bits of them onto rootstocks his lab manages on 15 acres in Puyallup. This process converts each outlying specimen into an isolated stand of genetically identical trees, preserving their unique DNA in what’s called a clonal holding block.

Now, those trees are part of a massive effort to pinpoint the tiny genetic variations that determine why some trees turn out better than others.

Six years ago, Chastagner and researchers at Washington State University, North Carolina State University and University of California, Davis jointly secured $1.3 million in funding from the U.S. Department of Agriculture to find genetic markers for Phytophthora root rot resistance and needle retention.

Chastagner’s graduate student, Katie McKeever, is collecting isolates of Phytophthora in various growing areas. By sequencing these samples and conducting pathogenicity trials, McKeever will contribute critical information to the team’s search for mechanisms of resistance in trees. Once the researchers find the relevant genetic markers, they can screen adult trees and select the most promising as seed sources for viable Christmas tree plantations.

The team will use similar techniques to resolve the matter of needle shedding. Chastagner’s multi-decade cataloging of Christmas trees with varying degrees of postharvest needle retention will give this part of the project a jump-start. By using these and other trees, scientists will be able to quickly identify needle-retentive gene sources so growers can produce desirable Christmas trees.

Through genetics research we can improve firs that are used for Christmas trees and ensure the genetic conservation of firs. There is much more to learn about conifer genetics, but as Chastagner said in the interview with Wired, “the potential for genetic improvement in these species is huge.”

19 Nov

Tocagen Appoints Lori Kunkel as Acting Chief Medical Officer

Tocagen (NASDAQ: TOCA), which is developing a gene therapy for brain cancer, said Thursday it has appointed board member Lori Kunkel as its acting chief medical officer effective Nov. 26. The San Diego-based company said its current CMO and senior vice president, Asha Das, is leaving as of Nov. 23 to “focus on unforeseen and immediate personal matters.”

Kunkel, who joined Tocagen’s board about three years ago, has previously held the CMO role at Loxo Oncology, Pharmacyclics, which was acquired by AbbVie (NYSE: ABBV), and Proteolix, which was acquired by Onyx Pharmaceuticals. Tocagen said it has initiated a search to… Read more »

UNDERWRITERS AND PARTNERS